ESTIMATION OF LEVEL OF SERUM CHOLINESTERASE IN THE PATIENTS OF LIVER DISEASES AND NON LIVER DISEASES

Abstract

Cholinesterase is an enzyme produced by liver, that catalyses the hydrolysis of neurotransmitter acetylcholine into choline and acetic acid. They are of two type’s acetylcholine esterase known as RBC cholinesterase (true cholinesterase) and plasma cholinesterase (pseudocholinsterase). Serum cholinesterase was found to be less than normal lower limit in 94.5% patients with liver diseases in our study. So assay of this enzyme is better than conventional test like total bilirubin etc. which are raised in other diseases also. Thus serum cholinesterase can be used as important biochemical parameter to distinguish liver diseases from non-liver diseases