MICROBIOLOGICAL PROFILE AND ANTIMICROBIAL SUSCEPTIBILITY PATTERN OF CHRONIC SUPPURATIVE OTITIS MEDIA IN TERTIARY CARE HOSPITAL

Abstract

Introduction: Chronic suppurative otitis media (CSOM) is defined as
chronic inflammation of middle ear cavity and mastoid cavity that may
present with recurrent ear discharge or otorrhoea through a tympanic
perforation. CSOM may develop in the first six years of life but can persist
during adulthood. It is most commonly prevalent in school children and in
low socio-economic status. Understanding of the microbiology of chronic
suppurative otitis media is important for appropriate and effective
treatment, and prevention of complications and antibiotic resistance.
Aim: To determine the microbiological profile of chronic suppurative otitis
media and its antimicrobial susceptibility pattern.
Materials and method: Present study includes 151 samples (Ear swabs)
obtained from CSOM patients of ENT department. Samples were processed
for bacterial and fungal growth and its antimicrobial susceptibility pattern
in tertiary care hospital.
Results: Out of 151 samples 124 (82.2%) were culture positive. Among
them 68 were males (54.84%) and 56 were females (45.16%). The most
predominant organism isolated was Staphylococcus aureus 36 (25%),
followed by Pseudomonas aeruginosa24 (16.66%). In this study fungal
organisms were isolated in 24 samples (16.66%) with predominant fungus
being Aspergillus niger 12(50 %). MSSA were highly sensitive to
Doxycycline, Ciprofloxacin and Gentamycin. Gram negative bacterias
showed high sensitivity to Piperacillin-Tazobactam, Amikacin, Meropenem
and Imipenem.
Conclusion: Now a day, CSOM is more prevalent in Adults. 20.58% of
Gramnegative bacteria were ESBL producers, 14.7% were AmpC
producers and 26.92% of gram positive were MRSAs. Hence CSOM
requires culture and sensitivity reports for effective management and to
prevent drug resistance.