DIAGNOSTIC CORRELATION OF MAGNETIC RESONANCE IMAGING AND CA 125 IN EVALUATION OF PRIMARY OVARIAN LESIONS

Authors

DR SRINIDHI SRINIVASAN , DR SVENKATESWARA RAO , DR ARUN PAUL , DR JONES LEKABOYINA, DR ARUN KUMMAR , DR SOUJANYA GERA Author

Keywords:

Ovarian carcinoma, CA 125, magnetic resonance imaging

Abstract

Ovarian cancer is usually asymptomatic, diagnosed at an advanced stage. Primary
ovarian tumours are known to show epithelial differentiation.
Tumour marker CA 125 is known to be mainly produced by tumour cells,
representing the neoplastic potential of these lesions. This study was done to evaluate
the association between serum CA 125 levels and magnetic resonance imaging
findings in predicting the potential for malignancy in primary ovarian lesions.
Retrospective cross-sectional study was done with 28 patients at department of
Radio-diagnosis, ASRAM medical college,Eluru. Out of 28 cases, histopathological
diagnosis showed 8 malignant,1 borderline and 19 benign lesions, with majority
being serous cystadenoma.Serum 125 was >35 IU/ml in 8 malignant,1 borderline and
7 benign lesions.The overall sensitivity was highest for serum CA 125 levels, while
the specificity was highest for multiloculated lesions followed by solid cystic lesions,
least being serum CA 125 levels.