A Study on the Prevalence of Pre-Eclampsia and the Effect of Serum Uric Acid Levels on Pregnancy Outcomes in Pre-Eclamptic Women: An observational study

Abstract

Background: Pre-eclampsia remains a major contributor to maternal and perinatal morbidity and mortality worldwide. Serum uric acid has been proposed as a marker for disease severity and poor pregnancy outcomes. Objective: To assess the prevalence of pre-eclampsia and evaluate the impact of elevated serum uric acid levels on pregnancy outcomes among women diagnosed with pre-eclampsia. Methods: This observational study involved 42 pregnant women diagnosed with pre-eclampsia. Serum uric acid levels were measured and correlated with maternal and fetal outcomes. Demographic profiles and risk factors were recorded. Results: Among the 42 pre-eclamptic women, 59.5% had elevated serum uric acid levels. Adverse maternal and fetal outcomes such as preterm labor, intrauterine growth restriction (IUGR), and caesarean section were significantly associated with higher uric acid levels. Conclusion: Elevated serum uric acid is associated with poor maternal and fetal outcomes in pre-eclampsia. Routine monitoring may help in early identification and better management of high-risk pregnancies.