Bacteriological Profile and Antibiogram of UTI in Pregnant Mother: A Study at Maternity hospital in North Bihar

Abstract

Introduction: Urinary tract infections frequently occurs in pregnant mothers. This
problem causes significant morbidity and increases healthcare expenditure . Three
common clinical manifestations of UTIs in pregnancy are: asymptomatic bacteriuria,
acute cystitis and acute pyelonephritis567. Escherichia coli is the most organism
isolated in pregnant mother having UTIs. All pregnant mothers should be screened
for UTIs in pregnancy and antibiotics should be started without delay. Urine culture
and antibiogram is the gold standard in diagnosing and treating UTIs123
.
Aims and Objectives: To know the bacteriological profile and Antibiogram of
urinary tract infection in pregnancy.
Material and Methods: all pregnant women who come to hospital for antenatal visits
are screened for UTI. All antenatal mother who comes to antenatal OPD were
randomly selected into the study (Upon verbal informed consent,) either had
symptoms suggestive of urinary tract infections clinically or without any symptoms
were only included. Mid-stream clean catch urine sample sent for microbiological
culture and sensitivity. We conducted a retrospective cohort study at Indra hospital,
supaul. The study population consisted of 200 women in the antenatal pts9,10,11
.
Results: A total of 200 urine samples were received from pregnant women and
processed in Microbiology laboratory from Jan to Dec 2024 .Among 200 samples,
85(42.5 %) samples yielded significant bacterial growth. E.coli (30, 35 %) was
isolated as predominant pathogen. E. Coli and Klebsiella were sensitive to
nitrofurantoin which can be used in pregnancy. Other organism isolated organisms
are Staphylococcus aureus, CONS, Enterococci and Acinetobacter.
Conclusion: This study showed that prevalence of UTI in pregnant women was
42.5%. It was also observed that E. coli (35%) was the most frequently isolated
bacteria. All pregnant women should be screened for UTI with a urine culture and
treated with according to results, significant predictors of bacteriuria in pregnancy
history include UTI and renal risk factors like Renal calculi, CKD and
nulliparity19,20,21. Women with UTI in pregnancy are more likely to have preterm
delivery. However, adequate management can minimize other complications like
pyelonephritis and adverse perinatal outcomes.