STUDY OF CARDIAC MANIFESTATIONS IN PATIENTS WITH CHRONIC LIVER DISEASE

Authors

Dr. Shashibhushan J , Dr. Rahul, Junior , Dr. Sadananda Adiga M.N Author

Keywords:

Chronic liver disease, Cirrhotic cardiomyopathy, Echocardiography, Atrial fibrillation, QTc prolongation, Child-Pugh score, Cardiac dysfunction

Abstract

Background: Chronic liver disease (CLD) is associated with multiple systemic
complications, of which cardiac manifestations are often underrecognized.
Objective: To evaluate the spectrum of cardiac manifestations in patients with
chronic liver disease and correlate findings with liver disease severity.
Methods: 100 patients with diagnosed CLD were evaluated clinically and with ECG,
chest X-ray, and echocardiography. Severity of liver disease was assessed using the
Child-Pugh classification.
Results:
•Mean age: 54.3 ± 9.7 years
•Male: 63%
•Cardiovascular symptoms: 41%
•ECG: Atrial fibrillation 21%, QTc prolongation 452.7 ± 24.1 ms, ST-T changes 23%
•Echo: LA dilation 15%, biventricular dilation 26%, valvular abnormalities 41%,
global LV dysfunction 77%, dilated cardiomyopathy 21%
•Child-Pugh Class C: 43%
•Strong correlation between liver disease severity and cardiac involvement.
Conclusion: Cardiac manifestations are common in CLD and increase with disease
severity. Routine cardiovascular screening in CLD patients is essential.