Recent Advances in Targeted Drug Delivery Systems: Innovations in Biopharmaceutical Sciences

Abstract

Background: The effectiveness of pharmaceutical treatments is often limited by factors such as poor bioavailability, systemic toxicity, and non-specific targeting. Targeted drug delivery (TDD) systems are a promising approach to overcome these challenges by enhancing the therapeutic efficacy and reducing side effects. Recent advancements in biopharmaceutical sciences have led to the development of novel drug delivery systems with improved precision and control.
Methods: This review explores the recent innovations in targeted drug delivery systems, focusing on their design, mechanisms of action, and therapeutic applications. Studies evaluating nanoparticles, liposomes, dendrimers, and targeted peptides as delivery platforms are discussed.
Results: Targeted drug delivery systems have demonstrated significant improvements in the targeted release of therapeutics, especially in cancer, autoimmune diseases, and gene therapy. The use of biocompatible carriers has improved the pharmacokinetics and biodistribution of drugs, leading to enhanced therapeutic outcomes.
Conclusion: Targeted drug delivery is a promising approach to improving the specificity and efficacy of treatments in various disease models. Continued research and clinical trials will be essential to translate these innovations into routine clinical practice.